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Date: 09 February 2016
Start time: 15:00 GMT (Greenwich Mean Time)
Duration: 1 Hour
9 days to go
Price: FREE
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Webinar Abstract
Title : Modern Catalysis: Academic Discovery to Industrial Application Date: Tuesday, 9th February 2016 Time: 15:00 GMT (Greenwich Mean Time) In the high-pressure environment of drug discovery, time is everything. Small and large molecule development is an increasingly complex process and reliance upon old methods is no longer a practical way to tackle new chemical challenges. While general catalytic methods do exist, substrate dependency makes it difficult to predict optimal conditions in practice. A thoughtful screening process is the best way to cover a large amount of chemical space quickly and efficiently. The webinar: Modern Catalysis: Academic Discovery to Industrial Application will feature Professor Stephen L.Buchwald (MIT), Dr Spencer D. Dreher (Merck&Co), and Dr Sarah L.J. Trice (Sigma-Aldrich). It will discuss the academic discovery of palladium precatalysts and their use as critical components in a robust high-throughput screening platform, developed in industry, and now commercially available from Sigma-Aldrich. This technology showcases the most widely used catalytic methods of synthetic chemists in both academia and industry, translated into an off-the-shelf screening system. Now, any bench chemist can rapidly run 24 unique microscale reactions in parallel with conditions tailored to ensure the best possible chance of success. If you would like to increase the probability of discovering your optimal reaction conditions while using a very small amount of valuable material then register now! You Will:
Is troubleshooting catalytic reactions in your multi-step synthesis a bottleneck that you struggle with in your workflow? If so, then this webinar is for you! Please join us
Presented By
 Professor Stephen L. BuchwaldCamille Dreyfus Professor of Chemistry MIT Stephen L. Buchwald received his Sc.B. degree from Brown University; he then entered Harvard University as a National Science Foundation Pre-doctoral Fellow where he received his Ph.D. He then was a Myron A. Bantrell postdoctoral fellow at Caltech with Professor Robert H. Grubbs where he studied titanocene methylenes as reagents in organic synthesis and the mechanism of Ziegler-Natta polymerization. In 1984 Stephen joined MIT as an Assistant Professor of Chemistry and was quickly promoted to the associate professor and to Professor, and was named the Camille Dreyfus Professor in 1997. In July 2015, Stephen became Associate Head of the Chemistry Department at MIT. During his time at MIT he received numerous honours including the Harold Edgerton Faculty Achievement Award of MIT and a MERIT award from the National Institutes of Health. He has also received an honorary doctoral degree from the University of South Florida as well as receiving the BBVA Frontiers in Knowledge Award in Basic Sciences. In 2016, he will receive the William H. Nichols Award from the New York Section of the American Chemical Society. He is the co-author of over 435 published or accepted papers and 47 issued patents. He currently serves as a consultant to a number of companies and is an associate editor of Advanced Synthesis and Catalysis.  Dr Spencer D. DreherPrinciple Scientist, Process Chemistry Merck&Co Dr Spencer D. Dreher obtained his B.S. in chemistry in 1994 from Macalester College. He then completed his Ph.D. in 1999 at Columbia University (T.J. Katz) followed by a postdoc from 1999-2000, also at Columbia University (J.L. Leighton). Spencer started his career as a process chemist at Merck&Co, where he worked from 2000-2006. In 2007, he joined the Process Chemistry Catalysis and Automation Group at Merck&Co, where he currently resides as a Principle Scientist in this group. Spencer specializes in high-throughput chemistry and applied catalysis for drug discovery and development. Additional Speakers: 
Dr Sarah L.J.Trice
Dr Sarah L.J, Trice received her B.S. in Chemistry from Northern Arizona University in 2005. She was recruited by Merck&Co's medicinal chemistry group in Philadelphia as a research scientist to develop novel HIV therapies. In 2009 she took employer-sponsored leave and joined Gary Molander's graduate research laboratory at the University of Pennsylvania to focus on the development and practical application of Bis-Boronic Acid (BBA) as a PhD candidate. After completing her PhD in 2012, she returned to Merck&Co, where she served as a Senior Scientist in Medicinal Chemistry and lead an extended interdepartmental catalytic screening center. Sarah recently brought her catalysis and organic chemistry expertise to Sigma-Aldrich and currently manages the Aldrich catalysis portfolio globally. |
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